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Restriction Site Tiling Analysis: accurate discovery and quantitative genotyping of genome-wide polymorphisms using nucleotide arrays

High-throughput genotype data can be used to identify genes important for local adaptation in wild populations, phenotypes in lab stocks, or disease-related traits in human medicine. Here we advance microarray-based genotyping for population genomics with Restriction Site Tiling Analysis. The approa...

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Bibliographic Details
Main Authors: Pespeni, Melissa H, Oliver, Thomas A, Manier, Mollie K, Palumbi, Stephen R
Format: Artigo
Language:Inglês
Published: BioMed Central 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2884547/
https://ncbi.nlm.nih.gov/pubmed/20403197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2010-11-4-r44
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