Generation and Characterization of Chimeric Antibodies against NS3, NS4, NS5, and Core Antigens of Hepatitis C Virus

Mouse-human chimeric antibodies (cAbs) against hepatitis C virus (HCV) core, NS3 (nonstructural), NS4, and NS5 antigens were developed as quality control (QC) reagents to replace the use of human sera/plasma for Abbott HCV immunoassays. The cAb retains the mouse monoclonal antibody (MAb) specificity...

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Autori principali: Tu, Bailin, Ziemann, Robert N., Tieman, Bryan C., Hawksworth, David J., Tyner, Joan, Scheffel, James, Pinkus, Mary S., Brophy, Susan E., Werneke, Jeffrey M., Gutierrez, Robin, White, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2010
Soggetti:
Clinical Laboratory Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2884432/
https://ncbi.nlm.nih.gov/pubmed/20427624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00068-10
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