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How the Load and the Nucleotide State Affect the Actin Filament Binding Mode of the Molecular Motor Myosin V

The interaction between actin and myosin V has been probed by measuring the unbinding force of individual actomyosin complexes using optical tweezers. Surprisingly, we found that in both the nucleotide-free and ADP-bound states single- and double-headed binding occurs with approximately the same pro...

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Main Authors: Mikhailenko, Sergey V., Oguchi, Yusuke, Ohki, Takashi, Shimozawa, Togo, Olivares, Adrian O., De La Cruz, Enrique M., Ishiwata, Shin’ichi
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2884403/
https://ncbi.nlm.nih.gov/pubmed/20552037
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