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Load-dependent ADP binding to myosins V and VI: Implications for subunit coordination and function

Dimeric myosins V and VI travel long distances in opposite directions along actin filaments in cells, taking multiple steps in a “hand-over-hand” fashion. The catalytic cycles of both myosins are limited by ADP dissociation, which is considered a key step in the walking mechanism of these motors. He...

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Bibliografische gegevens
Hoofdauteurs: Oguchi, Yusuke, Mikhailenko, Sergey V., Ohki, Takashi, Olivares, Adrian O., De La Cruz, Enrique M., Ishiwata, Shin'ichi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409399/
https://ncbi.nlm.nih.gov/pubmed/18509050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800564105
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