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Allele-specific genetic interactions between Mitf and Kit affect melanocyte development

The tyrosine kinase receptor KIT and the transcription factor MITF, each required for melanocyte development, have been shown to interact functionally both in vitro and in vivo. In vitro, KIT signaling leads to MITF phosphorylation, affecting MITF activity and stability. In vivo, the presence of the...

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Bibliografiske detaljer
Main Authors: Wen, Bin, Chen, Yu, Li, Huirong, Wang, Jin, Shen, Jie, Ma, Aobo, Qu, Jia, Bismuth, Keren, Debbache, Julien, Arnheiter, Heinz, Hou, Ling
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2884299/
https://ncbi.nlm.nih.gov/pubmed/20374522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1755-148X.2010.00699.x
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