An Unstable Targeted Allele of the Mouse Mitf Gene With a High Somatic and Germline Reversion Rate

The mouse Mitf gene encodes a transcription factor that is regulated by serine phosphorylation and is critical for the development of melanin-containing pigment cells. To test the role of phosphorylation at a particular serine, S73 in exon 2 of Mitf, we used a standard targeting strategy in mouse em...

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Bibliographic Details
Main Authors: Bismuth, Keren, Skuntz, Susan, Hallsson, Jón H., Pak, Evgenia, Dutra, Amalia S., Steingrímsson, Eiríkur, Arnheiter, Heinz
Format: Artigo
Language:Inglês
Published: Genetics Society of America 2008
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Investigations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2206076/
https://ncbi.nlm.nih.gov/pubmed/18202372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.107.081893
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