Triplex formation inhibits HER-2/neu transcription in vitro.

Triplex-forming oligonucleotides (TFOs) have been shown to bind to target DNA sequences in several human gene promoters such as the c-myc oncogene, the epidermal growth factor receptor, and the dihydrofolate reductase genes. TFOs have been shown to inhibit transcription in vitro and gene expression...

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Bibliografiske detaljer
Main Authors: Ebbinghaus, S W, Gee, J E, Rodu, B, Mayfield, C A, Sanders, G, Miller, D M
Format: Artigo
Sprog:Inglês
Udgivet: 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC288427/
https://ncbi.nlm.nih.gov/pubmed/7901237
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