The Mechanical Properties of PCNA: Implications for the Loading and Function of a DNA Sliding Clamp

Sliding clamps are toroidal proteins that encircle DNA and act as mobile platforms for DNA replication and repair machinery. To be loaded onto DNA, the eukaryotic sliding clamp Proliferating Cell Nuclear Antigen (PCNA) must be splayed open at one of the subunit-subunit interfaces by the ATP-dependen...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Adelman, Joshua L., Chodera, John D., Kuo, I-Feng W., Miller, Thomas F., Barsky, Daniel
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2010
Témata:
Protein
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2884248/
https://ncbi.nlm.nih.gov/pubmed/20550919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.03.056
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky