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The Mechanical Properties of PCNA: Implications for the Loading and Function of a DNA Sliding Clamp
Sliding clamps are toroidal proteins that encircle DNA and act as mobile platforms for DNA replication and repair machinery. To be loaded onto DNA, the eukaryotic sliding clamp Proliferating Cell Nuclear Antigen (PCNA) must be splayed open at one of the subunit-subunit interfaces by the ATP-dependen...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
The Biophysical Society
2010
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2884248/ https://ncbi.nlm.nih.gov/pubmed/20550919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.03.056 |
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