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Using a Single Fluorescent Reporter Gene to Infer Half-Life of Extrinsic Noise and Other Parameters of Gene Expression

Fluorescent and luminescent proteins are often used as reporters of transcriptional activity. Given the prevalence of noise in biochemical systems, the time-series data arising from these is of significant interest in efforts to calibrate stochastic models of gene expression and obtain information a...

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Main Authors: Komorowski, Michał, Finkenstädt, Bärbel, Rand, David
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2884236/
https://ncbi.nlm.nih.gov/pubmed/20550887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.03.032
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