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Direct physical study of kinetochore-microtubule interactions by reconstitution and interrogation with an optical force clamp

We detail our use of computer-controlled optical traps to study interactions between kinetochore components and dynamic microtubules. Over the last two decades optical traps have helped uncover the working principles of conventional molecular motors, such as kinesin and dynein, but only recently hav...

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Detalhes bibliográficos
Main Authors: Franck, Andrew D., Powers, Andrew F., Gestaut, Daniel R., Davis, Trisha N., Asbury, Charles L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2884078/
https://ncbi.nlm.nih.gov/pubmed/20096784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2010.01.020
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