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Label-free Fluorescent Functional DNA Sensors Using Unmodified DNA: A Vacant Site Approach
A general methodology to design label-free fluorescent functional DNA sensors using unmodified DNA via a vacant site approach is described. By extending one end of DNA with a loop, a vacant site that binds an extrinsic fluorophore, 2-amino-5,6,7-trimethyl-1,8-naphthyridine (ATMND) could be created a...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2884042/ https://ncbi.nlm.nih.gov/pubmed/20465295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac100244h |
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