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Radiotherapy Suppresses Angiogenesis in Mice through TGF-βRI/ALK5-Dependent Inhibition of Endothelial Cell Sprouting

BACKGROUND: Radiotherapy is widely used to treat cancer. While rapidly dividing cancer cells are naturally considered the main target of radiotherapy, emerging evidence indicates that radiotherapy also affects endothelial cell functions, and possibly also their angiogenic capacity. In spite of its c...

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Detalhes bibliográficos
Main Authors: Imaizumi, Natsuko, Monnier, Yan, Hegi, Monika, Mirimanoff, René-Olivier, Rüegg, Curzio
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2884035/
https://ncbi.nlm.nih.gov/pubmed/20552031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011084
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