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Generation of functional CD8+ T Cells by human dendritic cells expressing glypican-3 epitopes
BACKGROUND: Glypican 3 (GPC-3) is an oncofoetal protein that is expressed in most hepatocellular carcinomas (HCC). Since it is a potential target for T cell immunotherapy, we investigated the generation of functional, GPC-3 specific T cells from peripheral blood mononuclear cells (PBMC). METHODS: De...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2883974/ https://ncbi.nlm.nih.gov/pubmed/20465843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-29-48 |
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