Prostate apoptosis response protein 4 sensitizes human colon cancer cells to chemotherapeutic 5-FU through mediation of an NFκB and microRNA network

BACKGROUND: Diminished expression or activity of prostate apoptosis response protein 4 (Par-4) has been demonstrated in a number of cancers, although reports on Par-4 expression during colon cancer progression are lacking. An understanding of the molecular events in conjunction with the genetic netw...

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Detalhes bibliográficos
Main Authors: Wang, Bi-Dar, Kline, Christina Leah B, Pastor, Danielle M, Olson, Thomas L, Frank, Bryan, Luu, Truong, Sharma, Arun K, Robertson, Gavin, Weirauch, Matthew T, Patierno, Steven R, Stuart, Joshua M, Irby, Rosalyn B, Lee, Norman H
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883962/
https://ncbi.nlm.nih.gov/pubmed/20433755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-98
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