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Efficient Calculation of P-value and Power for Quadratic Form Statistics in Multilocus Association Testing
We address the asymptotic and approximate distributions of a large class of test statistics with quadratic forms used in association studies. The statistics of interest take the general form D = X(T) AX, where A is a general similarity matrix which may or may not be positive semi-definite, and X fol...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2883919/ https://ncbi.nlm.nih.gov/pubmed/20529017 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-1809.2010.00574.x |
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