Heparin regulates endothelin production through endothelium-derived nitric oxide in human endothelial cells.
Heparin shows blood pressure lowering effect in hypertensive patients and animal models. The present study examined the effect of heparin on vasoconstrictor endothelin-1 (ET-1) production in cultured human umbilical vein endothelial cells (ECs) to elucidate the mechanism of antihypertensive effect o...
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| Izdano u: | J Clin Invest |
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| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Clinical Investigation
1993
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288378/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8408661/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116805 |
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