Heparin regulates endothelin production through endothelium-derived nitric oxide in human endothelial cells.

Heparin shows blood pressure lowering effect in hypertensive patients and animal models. The present study examined the effect of heparin on vasoconstrictor endothelin-1 (ET-1) production in cultured human umbilical vein endothelial cells (ECs) to elucidate the mechanism of antihypertensive effect o...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Yokokawa, K, Tahara, H, Kohno, M, Mandal, A K, Yanagisawa, M, Takeda, T
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288378/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8408661/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116805
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