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Heparin regulates endothelin production through endothelium-derived nitric oxide in human endothelial cells.

Heparin shows blood pressure lowering effect in hypertensive patients and animal models. The present study examined the effect of heparin on vasoconstrictor endothelin-1 (ET-1) production in cultured human umbilical vein endothelial cells (ECs) to elucidate the mechanism of antihypertensive effect o...

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Bibliographische Detailangaben
Hauptverfasser: Yokokawa, K, Tahara, H, Kohno, M, Mandal, A K, Yanagisawa, M, Takeda, T
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1993
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC288378/
https://ncbi.nlm.nih.gov/pubmed/8408661
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