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Effect of danshen extract on the activity of CYP3A4 in healthy volunteers
AIMS: To assess the effect of danshen extract on CYP3A4 activity using midazolam as an in vivo probe. METHODS: A sequential, open-label, two-period pharmacokinetic interaction study design was used to compare midazolam pharmacokinetic parameters before and after 14 days of administration of danshen...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Blackwell Science Inc
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2883758/ https://ncbi.nlm.nih.gov/pubmed/20565457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2010.03624.x |
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