The phosphatase and tensin homologue deleted on chromosome 10 mediates radiosensitivity in head and neck cancer

BACKGROUND: For locally advanced squamous cell carcinoma of the head and neck (HNSCC), the recurrence rate after surgery and postoperative radiotherapy is between 20 and 40%, and the 5-year overall survival rate is ∼50%. Presently, no markers exist to accurately predict treatment outcome. Expression...

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Hlavní autoři: Pattje, W J, Schuuring, E, Mastik, M F, Slagter-Menkema, L, Schrijvers, M L, Alessi, S, van der Laan, B F A M, Roodenburg, J L N, Langendijk, J A, van der Wal, J E
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2010
Témata:
Molecular Diagnostics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883706/
https://ncbi.nlm.nih.gov/pubmed/20502457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605707
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