Ca(2+)/calmodulin dependent protein kinase II contributes to intracellular pH recovery from acidosis via Na(+)/H(+) exchanger activation

The Na(+)/H(+) exchanger (NHE-1) plays a key role in pH(i) recovery from acidosis and is regulated by pH(i) and the ERK1/2-dependent phosphorylation pathway. Since acidosis increases the activity of Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) in cardiac muscle, we examined whether CaMKII...

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Main Authors: Vila-Petroff, Martín, Mundiña-Weilenmann, Cecilia, Lezcano, Noelia, Snabaitis, Andrew K., Huergo, Maria Ana, Valverde, Carlos A., Avkiran, Metin, Mattiazzi, Alicia
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883686/
https://ncbi.nlm.nih.gov/pubmed/20026127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2009.12.007
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