Replicated Association between an IL28B Gene Variant and a Sustained Response to Pegylated Interferon and Ribavirin

BACKGROUND & AIMS: Patients with chronic hepatitis C virus (HCV) infections are treated with pegylated interferon and ribavirin (PEG-IFN/RBV), which is effective in less than 50% of those infected with HCV genotype 1. Genome-wide association studies have linked response to PEG-IFN/RBV with commo...

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Autori principali: McCarthy, Jeanette J., Li, Josephine H., Thompson, Alexander, Suchindran, Sunil, Lao, Xiang Qian, Patel, Keyur, Tillmann, Hans L., Muir, Andrew J., McHutchison, John G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883666/
https://ncbi.nlm.nih.gov/pubmed/20176026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.02.009
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