HCV regulates TGF-β1 production through the generation of reactive oxygen species in an NFκB-dependent manner

BACKGROUND & AIMS: The generation of oxidative stress and TGF-β1 production play important roles in liver fibrogenesis. We have previously shown that HCV increases hepatocyte TGF-β1 expression. However, the mechanisms by which this induction occurs have not been well studied. We explored the pos...

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Main Authors: Lin, Wenyu, Tsai, Wei-Lun, Shao, Run-Xuan, Wu, Guoyang, Peng, Lee F., Barlow, Lydia L., Chung, Woo Jin, Zhang, Leiliang, Zhao, Hong, Jang, Jae-Young, Chung, Raymond T.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883661/
https://ncbi.nlm.nih.gov/pubmed/20230822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.03.008
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