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HCV regulates TGF-β1 production through the generation of reactive oxygen species in an NFκB-dependent manner
BACKGROUND & AIMS: The generation of oxidative stress and TGF-β1 production play important roles in liver fibrogenesis. We have previously shown that HCV increases hepatocyte TGF-β1 expression. However, the mechanisms by which this induction occurs have not been well studied. We explored the pos...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2883661/ https://ncbi.nlm.nih.gov/pubmed/20230822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.03.008 |
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