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Casein Kinase 1 Functions as both Penultimate and Ultimate Kinase in Regulating Cdc25A Destruction

The Cdc25A protein phosphatase drives cell cycle transitions by activating cyclin-dependent protein kinases. Failure to regulate Cdc25A leads to deregulated cell cycle progression, bypass of cell cycle checkpoints and genome instability. Ubiquitin-mediated proteolysis plays an important role in bala...

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Библиографические подробности
Главные авторы: Honaker, Yuchi, Piwnica-Worms, Helen
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883652/
https://ncbi.nlm.nih.gov/pubmed/20348946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.96
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