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Relative contribution of Panton-Valentine leukocidin to PMN plasma membrane permeability and lysis caused by USA300 and USA400 culture supernatants

Panton-Valentine leukocidin (PVL) is a cytolytic toxin associated with severe community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infections. However, the relative contribution of PVL to host cell lysis during CA-MRSA infection remains unknown. Here we investigated the relativ...

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Bibliografiske detaljer
Main Authors: Graves, Shawna F., Kobayashi, Scott D., Braughton, Kevin R., Diep, Binh An, Chambers, Henry F., Otto, Michael, DeLeo, Frank R.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883622/
https://ncbi.nlm.nih.gov/pubmed/20172045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micinf.2010.02.005
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