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Polymorphonuclear leukocytes mediate Staphylococcus aureus Panton-Valentine leukocidin-induced lung inflammation and injury

Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) is epidemic in the United States, even rivaling HIV/AIDS in its public health impact. The pandemic clone USA300, like other CA-MRSA strains, expresses Panton-Valentine leukocidin (PVL), a pore-forming toxin that targets polym...

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Bibliographische Detailangaben
Hauptverfasser: Diep, Binh An, Chan, Liana, Tattevin, Pierre, Kajikawa, Osamu, Martin, Thomas R., Basuino, Li, Mai, Thuy T., Marbach, Helene, Braughton, Kevin R., Whitney, Adeline R., Gardner, Donald J., Fan, Xuemo, Tseng, Ching W., Liu, George Y., Badiou, Cedric, Etienne, Jerome, Lina, Gerard, Matthay, Michael A., DeLeo, Frank R., Chambers, Henry F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2010
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851770/
https://ncbi.nlm.nih.gov/pubmed/20231457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912403107
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