Post-translational Regulation of Runx2 in Bone and Cartilage

The Runx2 gene product is essential for mammalian bone development. In humans, Runx2 haploinsufficiency results in cleidocranial dysplasia, a skeletal disorder characterized by bone and dental abnormalities. At the molecular level, Runx2 acts as a transcription factor for genes expressed in hypertro...

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Bibliografiske detaljer
Main Authors: Jonason, J.H., Xiao, G., Zhang, M., Xing, L., Chen, D.
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2009
Fag:
Critical Reviews in Oral Biology & Medicine
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883617/
https://ncbi.nlm.nih.gov/pubmed/19734454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0022034509341629
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