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Post-translational Regulation of Runx2 in Bone and Cartilage
The Runx2 gene product is essential for mammalian bone development. In humans, Runx2 haploinsufficiency results in cleidocranial dysplasia, a skeletal disorder characterized by bone and dental abnormalities. At the molecular level, Runx2 acts as a transcription factor for genes expressed in hypertro...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
SAGE Publications
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2883617/ https://ncbi.nlm.nih.gov/pubmed/19734454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0022034509341629 |
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