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mTOR Activation, Lymphangiogenesis, and Estrogen-Mediated Cell Survival: The “Perfect Storm” of Pro-Metastatic Factors in LAM Pathogenesis

Research interest in lymphangioleiomyomatosis (LAM) has grown dramatically in the past decade, particularly among cancer biologists. There are at least two reasons for this: first, the discovery in the year 2000 that LAM cells carry TSC2 gene mutations, linking LAM with cellular pathways including t...

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Dettagli Bibliografici
Autori principali: Yu, Jane, Henske, Elizabeth Petri
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883473/
https://ncbi.nlm.nih.gov/pubmed/20235886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/lrb.2009.0020
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