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mTOR Activation, Lymphangiogenesis, and Estrogen-Mediated Cell Survival: The “Perfect Storm” of Pro-Metastatic Factors in LAM Pathogenesis

Research interest in lymphangioleiomyomatosis (LAM) has grown dramatically in the past decade, particularly among cancer biologists. There are at least two reasons for this: first, the discovery in the year 2000 that LAM cells carry TSC2 gene mutations, linking LAM with cellular pathways including t...

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Detalhes bibliográficos
Main Authors: Yu, Jane, Henske, Elizabeth Petri
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883473/
https://ncbi.nlm.nih.gov/pubmed/20235886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/lrb.2009.0020
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