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Saturable transport of insulin from plasma into the central nervous system of dogs in vivo. A mechanism for regulated insulin delivery to the brain.

By acting in the central nervous system, circulating insulin may regulate food intake and body weight. We have previously shown that the kinetics of insulin uptake from plasma into cerebrospinal fluid (CSF) can best be explained by passage through an intermediate compartment. To determine if transpo...

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Autori principali: Baura, G D, Foster, D M, Porte, D, Kahn, S E, Bergman, R N, Cobelli, C, Schwartz, M W
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1993
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC288346/
https://ncbi.nlm.nih.gov/pubmed/8408635
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