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Distinct nuclear proteins competing for an overlapping sequence of cyclic adenosine monophosphate and negative regulatory elements regulate tissue-specific mouse renin gene expression.

The mouse renin locus (Ren-1d) exhibits specific patterns of tissue expression. It is expressed in kidney but not submandibular gland (SMG). This locus contains a negative regulatory element (NRE) and a cAMP responsive element (CRE) that share an overlapping sequence. In the kidney, CRE binding prot...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Horiuchi, M, Pratt, R E, Nakamura, N, Dzau, V J
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1993
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288343/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8408633/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116770
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