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Visualizing Chromosome Mosaicism and Detecting Ethnic Outliers by the Method of “Rare” Heterozygotes and Homozygotes (RHH)

We describe a novel approach for evaluating SNP genotypes of a genome-wide association scan to identify “ethnic outlier” subjects whose ethnicity is different or admixed compared to most other subjects in the genotyped sample set. Each ethnic outlier is detected by counting a genomic excess of “rare...

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Hlavní autoři: McGinnis, Ralph E., Deloukas, Panos, McLaren, William M., Inouye, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883336/
https://ncbi.nlm.nih.gov/pubmed/20211853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq102
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