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Haplotype-based search for SNPs associated with differential type 1 diabetes risk among chromosomes carrying a specific HLA DRB1-DQA1-DQB1 haplotype

AIM: To test chromosomes carrying the same DRB1-DQA1-DQB1 haplotype for SNPs in the major histocompatibility complex (MHC) that might mark subgroups of the haplotype with different risks for type 1 diabetes (T1D). METHODS: Chromosomes from T1D children, their parents, and non-diabetic siblings in fa...

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Detalhes bibliográficos
Main Authors: McGinnis, R, McLaren, W, Ranganath, V, Whittaker, P, Hunt, S, Deloukas, P
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697815/
https://ncbi.nlm.nih.gov/pubmed/19143810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1463-1326.2008.00998.x
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