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MAG and OMgp Synergize with Nogo-A to Restrict Axonal Growth and Neurological Recovery after Spinal Cord Trauma

Functional recovery after adult CNS damage is limited in part by myelin inhibitors of axonal regrowth. Three molecules, Nogo-A, MAG, and OMgp, are produced by oligodendrocytes and share neuronal receptor mechanisms through NgR1 and PirB. While each has an axon-inhibitory role in vitro, their in vivo...

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Hlavní autoři: Cafferty, William B. J., Duffy, Philip, Huebner, Eric, Strittmatter, Stephen M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883258/
https://ncbi.nlm.nih.gov/pubmed/20484625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6239-09.2010
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