Demonstration of a critical role for free fatty acids in mediating counterregulatory stimulation of gluconeogenesis and suppression of glucose utilization in humans.

In vitro studies indicate that FFA compete with glucose as an oxidative fuel in muscle and, in addition, stimulate gluconeogenesis in liver. During counterregulation of hypoglycemia, plasma FFA increase and this is associated with an increase in glucose production and a suppression of glucose utiliz...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Fanelli, C, Calderone, S, Epifano, L, De Vincenzo, A, Modarelli, F, Pampanelli, S, Perriello, G, De Feo, P, Brunetti, P, Gerich, J E
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1993
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288319/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8408616/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116746
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