Demonstration of a critical role for free fatty acids in mediating counterregulatory stimulation of gluconeogenesis and suppression of glucose utilization in humans.

In vitro studies indicate that FFA compete with glucose as an oxidative fuel in muscle and, in addition, stimulate gluconeogenesis in liver. During counterregulation of hypoglycemia, plasma FFA increase and this is associated with an increase in glucose production and a suppression of glucose utiliz...

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Pubblicato in:	J Clin Invest
Autori principali:	Fanelli, C, Calderone, S, Epifano, L, De Vincenzo, A, Modarelli, F, Pampanelli, S, Perriello, G, De Feo, P, Brunetti, P, Gerich, J E
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1993
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288319/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8408616/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116746
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