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Small-molecule modulators of inward rectifier K(+) channels: recent advances and future possibilities

Inward rectifier potassium (Kir) channels have been postulated as therapeutic targets for several common disorders including hypertension, cardiac arrhythmias and pain. With few exceptions, however, the small-molecule pharmacology of this family is limited to nonselective cardiovascular and neurolog...

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Hlavní autoři: Bhave, Gautam, Lonergan, Daniel, Chauder, Brian A, Denton, Jerod S
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883187/
https://ncbi.nlm.nih.gov/pubmed/20543968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.10.179
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