Mitigation Effect of an FGF-2 Peptide on Acute Gastrointestinal Syndrome after High-Dose Ionizing Radiation

PURPOSE: Acute gastrointestinal syndrome (AGS) due to ionizing radiation (IR) causes death within 7 days. Currently, no satisfactory agent exists for mitigation of AGS. A peptide derived from the receptor binding domain of fibroblast growth factor 2 was synthesized (FGF-P) and its mitigation effect...

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Hoofdauteurs: Zhang, Lurong, Sun, Weimin, Wang, Jianjun, Zhang, Mei, Yang, Shanmin, Tian, Yeping, Vidyasagar, Sadasivan, Peña, Louis A, Zhang, Kunzhong, Cao, Yongbing, Yin, Liangjie, Wang, Wei, Zhang, Lei, Schaefer, Katherine L., Saubermann, Lawrence J., Swarts, Steven G., Fenton, Bruce M., Keng, Peter C., Okunieff, Paul
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883168/
https://ncbi.nlm.nih.gov/pubmed/20394858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2009.11.026
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