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Molecular basis and management of gastrointestinal stromal tumors
Molecularly targeted agents have dramatically impacted the management of several cancers. Targeting KIT has led to a new treatment paradigm in gastrointestinal stromal tumors (GISTs). KIT is a cell surface receptor with tyrosine kinases that, upon binding of its ligand, stem cell factor, activates v...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The WJG Press and Baishideng
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2883128/ https://ncbi.nlm.nih.gov/pubmed/20533592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v16.i22.2726 |
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