NOVEL AMYLOID-BETA SPECIFIC scFv and VH ANTIBODY FRAGMENTS FROM HUMAN AND MOUSE PHAGE DISPLAY ANTIBODY LIBRARIES

Anti-amyloid immunotherapy has been proposed as an appropriate therapeutic approach for Alzheimer’s disease (AD). Significant efforts have been made towards the generation and assessment of antibody-based reagents capable of preventing and clearing amyloid aggregates as well as preventing their syna...

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Main Authors: Medecigo, M., Manoutcharian, K., Vasilevko, V., Govezensky, T., Munguia, M. E., Becerril, B., Luz-Madrigal, A., Vaca, L., Cribbs, D. H., Gevorkian, G.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882999/
https://ncbi.nlm.nih.gov/pubmed/20451261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2010.03.023
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