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Microbiota innate stimulation is a prerequisite for T cell spontaneous proliferation and induction of experimental colitis

Little is known about how the microbiota regulates T cell proliferation and whether spontaneous T cell proliferation is involved in the pathogenesis of inflammatory bowel disease. In this study, we show that stimulation of innate pathways by microbiota-derived ligands and antigen-specific T cell sti...

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Библиографические подробности
Главные авторы: Feng, Ting, Wang, Lanfang, Schoeb, Trenton R., Elson, Charles O., Cong, Yingzi
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 2010
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882839/
https://ncbi.nlm.nih.gov/pubmed/20498021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20092253
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