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Structural basis of microtubule severing by the hereditary spastic paraplegia protein spastin
Spastin, the most common locus for mutations in hereditary spastic paraplegias1, and katanin are related microtubule-severing AAA ATPases2–6 involved in constructing neuronal7–10 and noncentrosomal7,11 microtubule arrays and in segregating chromosomes12,13. The mechanism by which spastin and katanin...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2882799/ https://ncbi.nlm.nih.gov/pubmed/18202664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature06482 |
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