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Estradiol suppresses NF-κB activation through coordinated regulation of let-7a and miR-125b in primary human macrophages
Previous findings suggest that estradiol has a suppressive effect on TNF-α, but the mechanism by which estradiol regulates TNF-α expression in primary human macrophages is unknown. Herein, we demonstrate that pretreatment of human macrophages with estradiol attenuates LPS-induced TNF-α expression th...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2882792/ https://ncbi.nlm.nih.gov/pubmed/20351193 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903463 |
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