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Role of endosomal membrane lipids and NPC2 in cholesterol transfer and membrane fusion
We examined the effect of Niemann-Pick disease type 2 (NPC2) protein and some late endosomal lipids [sphingomyelin, ceramide and bis(monoacylglycero)phosphate (BMP)] on cholesterol transfer and membrane fusion. Of all lipid-binding proteins tested, only NPC2 transferred cholesterol at a substantial...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The American Society for Biochemistry and Molecular Biology
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2882726/ https://ncbi.nlm.nih.gov/pubmed/20179319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M003822 |
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