The activation of factor X and prothrombin by recombinant factor VIIa in vivo is mediated by tissue factor.

The human coagulation system continuously generates very small quantities of Factor Xa and thrombin. Current evidence suggests that basal level activation of the hemostatic mechanism occurs via Factor VIIa-dependent activation of Factor X, but direct proof has not been available for the participatio...

詳細記述

書誌詳細

出版年:	J Clin Invest
主要な著者:	ten Cate, H, Bauer, K A, Levi, M, Edgington, T S, Sublett, R D, Barzegar, S, Kass, B L, Rosenberg, R D
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Clinical Investigation 1993
主題:	Research Article
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288259/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8376580/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116691
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