Ascorbic acid extends replicative life span of human embryonic fibroblast by reducing DNA and mitochondrial damages

Ascorbic acid has been reported to extend replicative life span of human embryonic fibroblast (HEF). Since the detailed molecular mechanism of this phenomenon has not been investigated, we attempted to elucidate. Continuous treatment of HEF cells with ascorbic acid (at 200 µM) from 40 population dou...

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Bibliographische Detailangaben
Hauptverfasser: Hwang, Won-Sang, Park, Seong-Hoon, Kim, Hyun-Seok, Kang, Hong-Jun, Kim, Min-Ju, Oh, Soo-Jin, Park, Jae-Bong, Kim, Jaebong, Kim, Sung Chan, Lee, Jae-Yong
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Korean Nutrition Society and The Korean Society of Community Nutrition 2007
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882584/
https://ncbi.nlm.nih.gov/pubmed/20535395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4162/nrp.2007.1.2.105
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