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WD40 Domain Divergence Is Important for Functional Differences between the Fission Yeast Tup11 and Tup12 Co-Repressor Proteins

We have previously demonstrated that subsets of Ssn6/Tup target genes have distinct requirements for the Schizosaccharomyces pombe homologs of the Tup1/Groucho/TLE co-repressor proteins, Tup11 and Tup12. The very high level of divergence in the histone interacting repression domains of the two prote...

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Hlavní autoři: Ferreira, Monica E., Berndt, Kurt D., Nilsson, Johan, Wright, Anthony P. H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882346/
https://ncbi.nlm.nih.gov/pubmed/20544037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011009
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