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Fabrication, characterization and in vitro evaluation of poly (D,L-lactide-co-glycolide) microparticles loaded with polyamidoamine-plasmid DNA dendriplexes for applications in non-viral gene delivery
We report, for the first time, on the preparation, characterization and in vitro testing of poly (D,L-lactide-co-glycolide) (PLGA) microparticles loaded with polyamidoamine (PAMAM)-plasmid DNA (pDNA) dendriplexes. Loading of pDNA into the PLGA microparticles increased by 150% when pDNA was first com...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2882054/ https://ncbi.nlm.nih.gov/pubmed/19670295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.21840 |
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