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Impaired Development of Atherosclerosis in Abcg1(−/−)Apoe(−/−) Mice; Identification of Specific Oxysterols that both Accumulate in Abcg1(−/−)Apoe(−/−) Tissues and Induce Apoptosis
OBJECTIVE: ABCG1 is highly expressed in macrophages and endothelial cells, two cell types that play important roles in the development of atherosclerosis. We generated Abcg1(−/−)Apoe(−/−) mice in order to understand the mechanism and cell types involved in changes in atherosclerosis following loss o...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2881948/ https://ncbi.nlm.nih.gov/pubmed/20299684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.110.205617 |
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