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Inactivation of the Tumor Suppressor Genes Causing the Hereditary Syndromes Predisposing to Head and Neck Cancer via Promoter Hypermethylation in Sporadic Head and Neck Cancers

Fanconi anemia (FA) and dyskeratosis congenita (DC) are rare inherited syndromes that cause head and neck squamous cell cancer (HNSCC). Prior studies of inherited forms of cancer have been extremely important in elucidating tumor suppressor genes inactivated in sporadic tumors. Here, we studied whet...

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Bibliografische gegevens
Hoofdauteurs: Smith, Ian M., Mithani, Suhail K., Mydlarz, Wojciech K., Chang, Steven S., Califano, Joseph A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: S. Karger AG 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881891/
https://ncbi.nlm.nih.gov/pubmed/20332657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000292104
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