Determination of genes and microRNAs involved in the resistance to fludarabine in vivo in chronic lymphocytic leukemia

BACKGROUND: Chronic lymphocytic leukemia (CLL) cells are often affected by genomic aberrations targeting key regulatory genes. Although fludarabine is the standard first line therapy to treat CLL, only few data are available about the resistance of B cells to this purine nucleoside analog in vivo. H...

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Main Authors: Moussay, Etienne, Palissot, Valérie, Vallar, Laurent, Poirel, Hélène A, Wenner, Thomas, El Khoury, Victoria, Aouali, Nasséra, Van Moer, Kris, Leners, Bernadette, Bernardin, François, Muller, Arnaud, Cornillet-Lefebvre, Pascale, Delmer, Alain, Duhem, Caroline, Ries, Fernand, van Dyck, Eric, Berchem, Guy
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2010
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881880/
https://ncbi.nlm.nih.gov/pubmed/20487546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-115
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